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PERSISTENT PAIN @ SALVEO

When pain persists, the plan should gradually rebuild capacity.

Assessment considers function, load, sleep, confidence in movement and factors affecting daily activity.

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When to seek urgent assessment
3D illustration of the human body with the brain, spinal cord and nerves highlighted.

PATHOLOGIES AND CLINICAL PRESENTATIONS

What may contribute to persistent pain?

These are the main clinical concerns, not a self-diagnosis list. Similar symptoms may have different sources and imaging findings do not always explain pain.

01

Primary and widespread chronic pain

Chronic primary pain
WHAT IT IS

Pain that persists or recurs for more than 3 months, causes significant distress or functional limitation, and is not better explained solely by another condition. It is real and may coexist with other diagnoses.

TYPICAL CLINICAL SYMPTOMS
  • Persistent pain or episodic flare-ups
  • Restriction in daily activity, work or sport
  • Sleep, energy, mood or concentration may be affected
Read more: Chronic primary pain
Chronic primary musculoskeletal pain
WHAT IT IS

Long-term pain in muscles, bones or joints where functional impact is not fully explained by structural findings. Assessment includes load, sensitivity, sleep and wider health context.

TYPICAL CLINICAL SYMPTOMS
  • Pain in one or several body regions
  • Increased sensitivity and reduced load tolerance
  • Symptom fluctuation without a clear new injury
Read more: Chronic primary musculoskeletal pain
Fibromyalgia
WHAT IT IS

A chronic widespread pain syndrome often accompanied by fatigue, unrefreshing sleep and cognitive difficulty. Diagnosis is clinical and requires consideration of other important explanations.

TYPICAL CLINICAL SYMPTOMS
  • Widespread pain and increased sensitivity
  • Fatigue and unrefreshing sleep
  • Stiffness, “fibro-fog”, headache or other fluctuating symptoms
Read more: Fibromyalgia
Pain presentation with nociplastic features
WHAT IT IS

Features suggesting altered pain processing when tissue or nerve damage does not fully explain the presentation. This describes a clinical mechanism, not a label based on pain intensity alone.

TYPICAL CLINICAL SYMPTOMS
  • Widespread pain or pain that changes location
  • Sensitivity to touch, pressure or multiple stimuli
  • Symptoms influenced by sleep, fatigue, stress and load
Read more: Pain presentation with nociplastic features
02

Spine and jaw

Persistent non-specific low-back pain
WHAT IT IS

Low-back pain lasting more than 3 months without a single specific cause that explains the complete presentation. Physical, health and psychosocial factors may all influence function.

TYPICAL CLINICAL SYMPTOMS
  • Low-back pain and stiffness
  • Difficulty with sitting, bending, lifting or walking
  • Symptoms fluctuating with activity, sleep or periods of stress
Read more: Persistent non-specific low-back pain
Persistent non-specific neck pain
WHAT IT IS

Long-term neck pain without one lesion that necessarily explains the symptoms. Posture, work, activity and individual sensitivity are assessed together.

TYPICAL CLINICAL SYMPTOMS
  • Neck and shoulder pain or stiffness
  • Restriction or lack of confidence when turning the head
  • Headache or fatigue during prolonged work
Read more: Persistent non-specific neck pain
Persistent radicular pain
WHAT IT IS

Neuropathic pain caused by irritation or injury of a nerve root that may continue after the original cause has been treated. Neurological examination distinguishes it from referred pain.

TYPICAL CLINICAL SYMPTOMS
  • Burning, electric or shooting pain into an arm or leg
  • Numbness, tingling or altered sensation
  • Weakness, reflex change or functional restriction
Read more: Persistent radicular pain
Persistent spinal pain syndrome after surgery
WHAT IT IS

Back or neck pain, with or without limb symptoms, that persists or recurs after spinal surgery. Causes may be multiple and require medical coordination.

TYPICAL CLINICAL SYMPTOMS
  • Persistent or recurrent pain after surgery
  • Nerve symptoms in an arm or leg
  • Reduced tolerance for walking, sitting, work or loading
Read more: Persistent spinal pain syndrome after surgery
Temporomandibular disorders
WHAT IT IS

Disorders of the jaw joint and chewing muscles that may produce persistent pain in the jaw, face or temple region.

TYPICAL CLINICAL SYMPTOMS
  • Pain in the jaw, cheek, ear region or temples
  • Clicking, locking or restricted mouth opening
  • Pain with chewing and tension in chewing muscles
Read more: Temporomandibular disorders
03

Joints, tendons and muscles

Symptomatic osteoarthritis
WHAT IT IS

A joint condition involving cartilage, bone and surrounding tissues. Imaging findings and pain severity do not always correspond.

TYPICAL CLINICAL SYMPTOMS
  • Load- and activity-related pain
  • Usually brief stiffness after rest
  • Restricted movement, weakness and functional difficulty
Read more: Symptomatic osteoarthritis
Persistent shoulder pain
WHAT IT IS

Long-term pain that may involve the rotator cuff, glenohumeral joint, nervous system or combined factors. Imaging alone does not identify the symptom source.

TYPICAL CLINICAL SYMPTOMS
  • Pain when lifting or using the arm
  • Night pain or pain when lying on the shoulder
  • Weakness and restriction in work, dressing or sport
Read more: Persistent shoulder pain
Persistent tendinopathy
WHAT IT IS

A tendon capacity and load-related condition that may persist for months, affecting the Achilles, patellar, gluteal, rotator-cuff or other tendons.

TYPICAL CLINICAL SYMPTOMS
  • Localised pain during tendon loading
  • Stiffness after rest or at the start of activity
  • Reduced strength and tolerance for repeated activity
Read more: Persistent tendinopathy
Persistent hip and pelvic pain
WHAT IT IS

Long-term pain that may arise from the hip joint, gluteal tendons, abdominal wall, pelvis or referred sources. Location alone is not a diagnosis.

TYPICAL CLINICAL SYMPTOMS
  • Groin, lateral-hip, buttock or pelvic pain
  • Difficulty walking, using stairs, sitting or side-lying
  • Restricted movement and reduced load tolerance
Read more: Persistent hip and pelvic pain
Persistent knee pain
WHAT IT IS

Pain continuing after an injury, a period of overload or without one clear cause. Meniscal, patellofemoral, osteoarthritic and pain-sensitivity presentations are differentiated clinically.

TYPICAL CLINICAL SYMPTOMS
  • Pain with walking, stairs, sit-to-stand or running
  • Swelling or stiffness that may fluctuate
  • Weakness and reduced confidence in the affected knee
Read more: Persistent knee pain
Persistent myofascial pain
WHAT IT IS

Regional pain associated with muscles and surrounding tissues, often with tenderness and reduced tolerance. Tender points alone should not be treated as proof of cause.

TYPICAL CLINICAL SYMPTOMS
  • Local or referred pain from a muscular region
  • Pressure sensitivity and stiffness
  • Pain with prolonged use or repeated loading
Read more: Persistent myofascial pain
04

Neuropathic and regional pain

Peripheral neuropathic pain
WHAT IT IS

Pain caused by a lesion or disease of the peripheral somatosensory nervous system. Causes may be metabolic, traumatic, infectious, toxic or mechanical.

TYPICAL CLINICAL SYMPTOMS
  • Burning, tingling, electric or shooting pain
  • Numbness or reduced sensation
  • Pain from light touch and sometimes weakness
Read more: Peripheral neuropathic pain
Compression neuropathy
WHAT IT IS

Persistent compression or irritation of a peripheral nerve, such as carpal, cubital or tarsal tunnel syndrome. Symptoms often follow the nerve territory.

TYPICAL CLINICAL SYMPTOMS
  • Numbness, tingling or burning in a defined distribution
  • Night symptoms or symptoms in particular positions
  • Weakness of grip, foot or involved muscles
Read more: Compression neuropathy
Post-herpetic neuralgia
WHAT IT IS

Neuropathic pain that persists in the affected area after shingles, even once the rash and blisters have healed.

TYPICAL CLINICAL SYMPTOMS
  • Burning or shooting pain in a band of skin
  • Marked sensitivity to touch or clothing
  • Numbness, itching or altered sensation
Read more: Post-herpetic neuralgia
Complex regional pain syndrome (CRPS)
WHAT IT IS

Persistent regional pain disproportionate to an injury or operation, with sensory, vasomotor, sudomotor and motor changes. Early multidisciplinary recognition and care are important.

TYPICAL CLINICAL SYMPTOMS
  • Burning pain and marked sensitivity
  • Temperature, colour, sweating or swelling changes
  • Stiffness, weakness and restricted limb use
Read more: Complex regional pain syndrome (CRPS)
Phantom-limb pain
WHAT IT IS

Pain perceived in the amputated part of a limb. It differs from residual-limb pain and may coexist with prosthetic or wound problems.

TYPICAL CLINICAL SYMPTOMS
  • Burning, squeezing, cramping or electric pain in the missing limb
  • Fluctuating episodes or continuous pain
  • Sleep disturbance and difficulty using a prosthesis
Read more: Phantom-limb pain
05

After trauma and procedures

Chronic post-surgical pain
WHAT IT IS

Pain that develops or increases after surgery and persists beyond expected healing, after infection, mechanical complications and other causes have been considered.

TYPICAL CLINICAL SYMPTOMS
  • Pain near the operated area or in a nerve distribution
  • Scar sensitivity, numbness or burning
  • Functional restriction persisting beyond the expected recovery phase
Read more: Chronic post-surgical pain
Chronic post-traumatic pain
WHAT IT IS

Pain continuing after a fracture, dislocation, sprain, accident or soft-tissue injury after the acute phase. It may include nociceptive and neuropathic components.

TYPICAL CLINICAL SYMPTOMS
  • Persistent pain in the injured region
  • Stiffness, weakness or reduced load tolerance
  • Fear of movement or difficulty returning to activity
Read more: Chronic post-traumatic pain
Pain after fracture and immobilisation
WHAT IT IS

Pain and restriction may continue after bone union because of stiffness, weakness, sensitivity or complications. Non-union and fixation failure should be excluded when suspected.

TYPICAL CLINICAL SYMPTOMS
  • Pain with loading or at end range
  • Stiffness and weakness after immobilisation
  • Swelling or function that is not progressing as expected
Read more: Pain after fracture and immobilisation
Persistent scar pain and sensitivity
WHAT IT IS

A scar may remain sensitive because of small-nerve irritation, adhesion or heightened sensory response. The wound should be healed and free of infection signs.

TYPICAL CLINICAL SYMPTOMS
  • Pain or burning over or around the scar
  • Sensitivity to touch, clothing or pressure
  • Pulling and restriction with tissue movement
Read more: Persistent scar pain and sensitivity
06

Secondary causes and warning signs

Inflammatory arthritis
WHAT IT IS

Autoimmune disease such as rheumatoid or psoriatic arthritis may cause chronic pain, joint inflammation and progressive damage. Rheumatology assessment and management are required.

TYPICAL CLINICAL SYMPTOMS
  • Swelling, warmth and pain in several joints
  • Prolonged morning stiffness
  • Fatigue, reduced energy or systemic flares
Read more: Inflammatory arthritis
Axial spondyloarthritis
WHAT IT IS

An inflammatory condition mainly affecting the sacroiliac joints and spine. Inflammatory back pain should not be treated as mechanical pain without medical assessment.

TYPICAL CLINICAL SYMPTOMS
  • Back or buttock pain improving with movement
  • Prolonged morning stiffness and night pain
  • Younger onset, alternating buttock pain or other inflammatory features
Read more: Axial spondyloarthritis
Osteoporotic vertebral fracture
WHAT IT IS

A vertebral compression fracture, sometimes after minor or no clear trauma in weakened bone. New pain or postural change requires medical assessment.

TYPICAL CLINICAL SYMPTOMS
  • New focal back pain
  • Pain with standing, walking or position change
  • Loss of height or increasing kyphosis
Read more: Osteoporotic vertebral fracture
Spinal or joint infection
WHAT IT IS

Bone, disc or joint infection may present as persistent pain and requires urgent medical assessment, laboratory tests and imaging when indicated.

TYPICAL CLINICAL SYMPTOMS
  • Severe progressive pain, often also at rest
  • Fever, chills or systemic illness
  • A hot swollen joint or risk factors for infection
Read more: Spinal or joint infection
Cancer-related pain
WHAT IT IS

Pain from a primary or metastatic tumour may resemble musculoskeletal pain. Suspicion requires medical assessment and is not managed with physiotherapy alone.

TYPICAL CLINICAL SYMPTOMS
  • Progressive, constant or unusual pain for the person
  • Unexplained weight loss, fatigue or a history of cancer
  • Night pain accompanied by other systemic features
Read more: Cancer-related pain
Cauda equina or spinal-cord compression
WHAT IT IS

Neurological compression that may cause permanent deficit and requires emergency assessment. Existing chronic pain does not exclude a new acute change.

TYPICAL CLINICAL SYMPTOMS
  • New bladder or bowel disturbance
  • Saddle numbness or progressive limb weakness
  • New gait difficulty, loss of balance or change in hand coordination
Read more: Cauda equina or spinal-cord compression

Descriptions are for orientation. Diagnosis follows history, clinical examination and, only when indicated, imaging or laboratory tests.

ASSESSMENT

What do we examine?

Tests are selected according to history, symptoms and goals rather than a fixed package.

  • Functional goals and limitations
  • Current activity tolerance
  • Aggravating and easing factors
  • A progressive, monitorable plan

REHABILITATION PATHWAY

01Complete history

Progress, previous care and the effect on daily life are reviewed.

02Goals

Functions the person wants to regain are defined.

03Tolerance baseline

A manageable and repeatable activity level is established.

04Graded progress

Load increases in measurable steps while response is monitored.

05Self-management

The plan aims to build confidence, consistency and strategies for fluctuations.

COMMON QUESTIONS

Before assessment.

General guidance for this concern; individual decisions follow examination.

Does persistent pain mean damage is worsening?

Not necessarily. Pain and tissue damage do not always change in parallel; new changes should still be assessed.

Should I exercise when symptoms fluctuate?

Activity can be built from a stable baseline and progressed according to individual response.

What role does sleep play?

Sleep, stress, load and recovery may affect tolerance and should be considered.

How quickly should change occur?

Goals focus on function and capacity; the pace varies with history and response.

PHYSIOTHERAPY

Clinical cases

Assessment, treatment and follow-up from individual rehabilitation cases.

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